Mouse Acvr1 activation kit by CRISPRa

CAT#: GA200052

Acvr1 CRISPRa kit - CRISPR gene activation of mouse activin A receptor, type 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Acvr1
Locus ID 11477
Kit Components

GA200052G1, Acvr1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200052G2, Acvr1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200052G3, Acvr1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001110204, NM_001110205, NM_007394, NM_001355048, NM_001355049
Synonyms ActR-I; ActRIA; Acvr; Acvrlk2; Alk-2; ALK2; Alk8; D330013D15Rik; SKR1; Tsk7L
Summary On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin. May be involved in left-right pattern formation during embryogenesis.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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