Mouse Ak2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ak2
Locus ID	11637
Kit Components	GA200141G1, Ak2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200141G2, Ak2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200141G3, Ak2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001033966, NM_016895, NR_138540
Synonyms	Ak-2; D4Ertd220e
Summary	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. Plays a key role in hematopoiesis.[UniProtKB/Swiss-Prot Function]

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