Mouse Atoh1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Atoh1
Locus ID	11921
Kit Components	GA200309G1, Atoh1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200309G2, Atoh1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200309G3, Atoh1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007500
Synonyms	bHLHa14; Hath1; MATH-1; Math1
Summary	Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription.[UniProtKB/Swiss-Prot Function]

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