Mouse C5ar1 activation kit by CRISPRa

CAT#: GA200470

C5ar1 CRISPRa kit - CRISPR gene activation of mouse complement component 5a receptor 1



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol C5ar1
Locus ID 12273
Kit Components

GA200470G1, C5ar1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA200470G2, C5ar1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA200470G3, C5ar1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001173550, NM_007577
Synonyms C5aR; C5r1; Cd88; D7Msu1
Summary Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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