Mouse Casp7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Casp7
Locus ID	12369
Kit Components	GA200540G1, Casp7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200540G2, Casp7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200540G3, Casp7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007611
Synonyms	AI314680; caspase-7; CMH-1; ICE-IAP3; mCASP-7; Mch3
Summary	Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Overexpression promotes programmed cell death (By similarity).[UniProtKB/Swiss-Prot Function]

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