Mouse Cbx1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cbx1
Locus ID	12412
Kit Components	GA200568G1, Cbx1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200568G2, Cbx1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200568G3, Cbx1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_007622, NM_001362560, NM_001362561, NM_001362563, NM_001362564
Synonyms	Cbx; Cbx-rs2; E430007M08Rik; HP1B; Hp1beta; M31; MOD1
Summary	Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.[UniProtKB/Swiss-Prot Function]

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