Mouse Cdkn1c activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdkn1c
Locus ID	12577
Kit Components	GA200678G1, Cdkn1c gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200678G2, Cdkn1c gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200678G3, Cdkn1c gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001161624, NM_009876, NM_001354981
Synonyms	AL024410; CDKI; Kip2; p57(kip2); p57Kip2
Summary	Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.[UniProtKB/Swiss-Prot Function]

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