Mouse Chrm1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chrm1
Locus ID	12669
Kit Components	GA200724G1, Chrm1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200724G2, Chrm1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200724G3, Chrm1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001112697, NM_007698
Synonyms	Chrm-1; M1; M1R
Summary	The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.[UniProtKB/Swiss-Prot Function]

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