Mouse Creb1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Creb1
Locus ID	12912
Kit Components	GA200866G1, Creb1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200866G2, Creb1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200866G3, Creb1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001037726, NM_009952, NM_133828
Synonyms	2310001E10Rik; 3526402H21Rik; AV083133; Creb; Creb-1
Summary	Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.[UniProtKB/Swiss-Prot Function]

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