Mouse Crhr2 activation kit by CRISPRa
CAT#: GA200874
Crhr2 CRISPRa kit - CRISPR gene activation of mouse corticotropin releasing hormone receptor 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Crhr2 |
Locus ID | 12922 |
Kit Components | GA200874G1, Crhr2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA200874G2, Crhr2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA200874G3, Crhr2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001288618, NM_001288619, NM_001288620, NM_009953 |
Synonyms | CRF-R2; Crfr2; CRFR2alpha; CRFR2beta |
Summary | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN503824 | Crhr2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |