Mouse Esr2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Esr2
Locus ID	13983
Kit Components	GA201300G1, Esr2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201300G2, Esr2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201300G3, Esr2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010157, NM_207707, NR_104386
Synonyms	ERbeta; ER[b]; Estrb
Summary	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1 (ER-alpha), and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner. May play a role in ovarian follicular growth and maturation.[UniProtKB/Swiss-Prot Function]

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