Mouse Fcer1a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Fcer1a
Locus ID	14125
Kit Components	GA201371G1, Fcer1a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201371G2, Fcer1a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201371G3, Fcer1a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_010184
Synonyms	Fce1a; fcepsilonri; FcERI; Fcr-5
Summary	Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.[UniProtKB/Swiss-Prot Function]

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