Mouse Frat1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Frat1
Locus ID	14296
Kit Components	GA201472G1, Frat1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201472G2, Frat1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201472G3, Frat1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008043
Synonyms	AW060382
Summary	Positively regulates the Wnt signaling pathway by stabilizing beta-catenin through the association with GSK-3. May play a role in tumor progression and collaborate with PIM1 and MYC in lymphomagenesis.[UniProtKB/Swiss-Prot Function]

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