Mouse Aktip activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aktip
Locus ID	14339
Kit Components	GA201484G1, Aktip gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201484G2, Aktip gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201484G3, Aktip gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302266, NM_001302267, NM_001302268, NM_001302337, NM_010241, NM_001358934, NM_001358935, NM_001358936, NM_001358937, NM_001358938
Synonyms	AL023020; Fif; Ft; Ft1; Fts
Summary	Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade (By similarity).[UniProtKB/Swiss-Prot Function]

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