Mouse Grid2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grid2
Locus ID	14804
Kit Components	GA201735G1, Grid2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201735G2, Grid2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201735G3, Grid2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008167
Synonyms	B230104L07Rik; cpr; GluD2; GluRdelta2; ho; Lc; Lc; MMS10-AC; Ms10ac; nmf408; tpr
Summary	Receptor for glutamate. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. The postsynaptic actions of Glu are mediated by a variety of receptors that are named according to their selective agonists. Promotes synaptogenesis and mediates the D-Serine-dependent long term depression signals and AMPA receptor endocytosis of cerebellar parallel fiber-Purkinje cell (PF-PC) synapses through the beta-NRX1-CBLN1-GRID2 triad complex.[UniProtKB/Swiss-Prot Function]

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