Mouse Gspt1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gspt1
Locus ID	14852
Kit Components	GA201756G1, Gspt1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201756G2, Gspt1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201756G3, Gspt1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001130008, NM_146066
Synonyms	AI314175; AI326449; AV307676; C79774; G1st; Gst-1
Summary	Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth (By similarity). Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons (By similarity).[UniProtKB/Swiss-Prot Function]

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