Mouse Gucy2e activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gucy2e
Locus ID	14919
Kit Components	GA201786G1, Gucy2e gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201786G2, Gucy2e gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201786G3, Gucy2e gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008192
Synonyms	GC-E; GC1; ROS-GC1
Summary	Catalyzes the synthesis of cyclic GMP (cGMP) in rods and cones of photoreceptors. Plays an essential role in phototransduction, by mediating cGMP replenishment (PubMed:21598940). May also participate in the trafficking of membrane-asociated proteins to the photoreceptor outer segment membrane (PubMed:17255100).[UniProtKB/Swiss-Prot Function]

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