Mouse Hmgcr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hmgcr
Locus ID	15357
Kit Components	GA201920G1, Hmgcr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA201920G2, Hmgcr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA201920G3, Hmgcr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008255, NM_001360165, NM_001360166
Synonyms	HMG-CoAR; Red
Summary	Transmembrane glycoprotein that is the rate-limiting enzyme in cholesterol biosynthesis as well as in the biosynthesis of nonsterol isoprenoids that are essential for normal cell function including ubiquinone and geranylgeranyl proteins.[UniProtKB/Swiss-Prot Function]

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