Mouse Il18r1 activation kit by CRISPRa
CAT#: GA202139
Il18r1 CRISPRa kit - CRISPR gene activation of mouse interleukin 18 receptor 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Il18r1 |
Locus ID | 16182 |
Kit Components | GA202139G1, Il18r1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202139G2, Il18r1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202139G3, Il18r1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001161842, NM_001161843, NM_008365 |
Synonyms | Il1rrp; Il18ralpha |
Summary | Within the IL18 receptor complex, responsible for the binding of the proinflammatory cytokine IL18, but not IL1A nor IL1B. Involved in IL18-mediated IFNG synthesis from T-helper 1 (Th1) cells (By similarity). Contributes to IL18-induced cytokine production, either independently of SLC12A3, or as a complex with SLC12A3 (PubMed:26099046).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN508246 | Il18r1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |