Mouse Il2ra activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Il2ra
Locus ID	16184
Kit Components	GA202141G1, Il2ra gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202141G2, Il2ra gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202141G3, Il2ra gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008367
Synonyms	CD25; Il2r; Ly-43
Summary	Receptor for interleukin-2. The receptor is involved in the regulation of immune tolerance by controlling regulatory T cells (TREGs) activity. TREGs suppress the activation and expansion of autoreactive T-cells.[UniProtKB/Swiss-Prot Function]

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