Mouse Kcnq2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kcnq2
Locus ID	16536
Kit Components	GA202285G1, Kcnq2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202285G2, Kcnq2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202285G3, Kcnq2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001003824, NM_001003825, NM_001006668, NM_001006669, NM_001006674, NM_001006675, NM_001006676, NM_001006677, NM_001006678, NM_001006679, NM_001006680, NM_001302888, NM_010611
Synonyms	HNSPC; KQT2; Nmf134
Summary	Associates with KCNQ3 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability.[UniProtKB/Swiss-Prot Function]

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