Mouse Ldlr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ldlr
Locus ID	16835
Kit Components	GA202435G1, Ldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202435G2, Ldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202435G3, Ldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001252658, NM_001252659, NM_010700
Synonyms	Hlb301
Summary	Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits.[UniProtKB/Swiss-Prot Function]

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