Mouse Llgl1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Llgl1
Locus ID	16897
Kit Components	GA202467G1, Llgl1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202467G2, Llgl1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202467G3, Llgl1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001159404, NM_001159405, NM_008502
Synonyms	AI325176; Lgl1; Llglh; Mgl1
Summary	Cortical cytoskeleton protein found in a complex involved in maintaining cell polarity and epithelial integrity. Involved in the regulation of mitotic spindle orientation, proliferation, differentiation and tissue organization of neuroepithelial cells. Involved in axonogenesis through RAB10 activation thereby regulating vesicular membrane trafficking toward the axonal plasma membrane.[UniProtKB/Swiss-Prot Function]

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