Mouse Mitf activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mitf
Locus ID	17342
Kit Components	GA202661G1, Mitf gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202661G2, Mitf gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202661G3, Mitf gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113198, NM_001178049, NM_008601
Synonyms	BCC2; Bhlhe32; bw; Gsfbcc2; mi; vit; Vitiligo; Wh
Summary	This transcription factor serves at a critical point between extracellular signaling and downstream targets in cell specification in early eye and neural crest development. Mutant alleles have been identified that generate distinct phenotypes. Some of these alleles are being used to model the human diseases Waardenburg syndrome IIa and Tietz syndrome. [provided by RefSeq, Jul 2008]

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