Mouse Nfatc2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nfatc2
Locus ID	18019
Kit Components	GA202871G1, Nfatc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA202871G2, Nfatc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA202871G3, Nfatc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001037177, NM_001037178, NM_001136073, NM_001291168, NM_001291169, NM_001291170, NM_001291171, NM_001291172, NM_001291173, NM_001291174, NM_001291175, NM_001291176, NM_001291177, NM_001291178, NM_001291179, NM_010899, NR_111897, NR_111898
Synonyms	AI607462; NF-ATc2; NF-ATp; NFAT1; NFAT1-D; Nfatp
Summary	Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2, IL-3, IL-4, TNF-alpha or GM-CSF. Promotes invasive migration through the activation of GPC6 expression and WNT5A signaling pathway.[UniProtKB/Swiss-Prot Function]

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