Mouse Peg3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Peg3
Locus ID	18616
Kit Components	GA203171G1, Peg3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA203171G2, Peg3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA203171G3, Peg3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_008817
Synonyms	AL022617; ASF-1; End4; Gcap4; mKIAA0287; Pw1; Zfp102
Summary	Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B. Plays a role in regulating maternal behavior and offspring growth.[UniProtKB/Swiss-Prot Function]

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