Mouse Rbpms activation kit by CRISPRa

CAT#: GA203593

Rbpms CRISPRa kit - CRISPR gene activation of mouse RNA binding protein gene with multiple splicing



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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经常一起买 (1)
Anti-RBPMS Antibody
    • 100 ul

CNY 5,325.00

Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Rbpms
Locus ID 19663
Kit Components

GA203593G1, Rbpms gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA203593G2, Rbpms gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA203593G3, Rbpms gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001042674, NM_001042675, NM_001286168, NM_019733
Synonyms 2010300K22Rik; 2700019M19Rik; AU017537; hermes; RBP-MS
Summary Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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