Mouse Tnfsf12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf12
Locus ID	21944
Kit Components	GA204399G1, Tnfsf12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204399G2, Tnfsf12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204399G3, Tnfsf12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_011614
Synonyms	Apo3l; Dr3l; Dr3lg; Tweak
Summary	Binds to FN14 and possibly also to TNRFSF12/APO3. Weak inducer of apoptosis in some cell types. Mediates NF-kappa-B activation. Promotes angiogenesis and the proliferation of endothelial cells. Also involved in induction of inflammatory cytokines. Promotes IL8 secretion (By similarity).[UniProtKB/Swiss-Prot Function]

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