Mouse Tnfsf10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf10
Locus ID	22035
Kit Components	GA204440G1, Tnfsf10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204440G2, Tnfsf10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204440G3, Tnfsf10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009425
Synonyms	A330042I21Rik; AI448571; APO-2L; Ly81; TL2; Tnlg6a; Trail
Summary	Cytokine that binds to TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and possibly also to TNFRSF11B/OPG. Induces apoptosis. Its activity may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4 and TNFRSF11B/OPG that cannot induce apoptosis.[UniProtKB/Swiss-Prot Function]

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