Mouse Unc13b activation kit by CRISPRa
CAT#: GA204544
Unc13b CRISPRa kit - CRISPR gene activation of mouse unc-13 homolog B
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Unc13b |
Locus ID | 22249 |
Kit Components | GA204544G1, Unc13b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204544G2, Unc13b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204544G3, Unc13b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001081413, NM_001310758, NM_021468 |
Synonyms | Munc13-1; Munc13-2; Unc13a; Unc13h1; Unc13h2 |
Summary | Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP) (By similarity). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN518701 | Unc13b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |