Mouse Upp1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Upp1
Locus ID	22271
Kit Components	GA204555G1, Upp1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204555G2, Upp1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204555G3, Upp1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001159401, NM_001159402, NM_009477
Synonyms	AI325217; UdRPase; Up; UPase; Upp
Summary	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate (PubMed:7744869). The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.[UniProtKB/Swiss-Prot Function]

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