Mouse Ush2a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ush2a
Locus ID	22283
Kit Components	GA204562G1, Ush2a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204562G2, Ush2a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204562G3, Ush2a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_021408
Synonyms	A930011D15Rik; A930037M10Rik; Gm676; Gm983; Mush2a; Usherin; Ushrn
Summary	Involved in hearing and vision as member of the USH2 complex (PubMed:20502675). In the inner ear, required for the maintenance of hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells (PubMed:20502675, PubMed:24334608). In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport (PubMed:20502675).[UniProtKB/Swiss-Prot Function]

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