Mouse Xrcc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Xrcc1
Locus ID	22594
Kit Components	GA204660G1, Xrcc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204660G2, Xrcc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204660G3, Xrcc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_009532, NM_001360170, NM_001360168, NM_001360169
Synonyms	Xrcc-1
Summary	Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (By similarity). Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity (PubMed:28002403).[UniProtKB/Swiss-Prot Function]

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