Mouse Ing1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ing1
Locus ID	26356
Kit Components	GA204915G1, Ing1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204915G2, Ing1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204915G3, Ing1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001302451, NM_001302457, NM_001302458, NM_001302459, NM_001302460, NM_011919
Synonyms	2610028J21Rik; AA407184; AI875420; mING1h; p33Ing1; p37Ing1b
Summary	Isoform 1 inhibits p53-dependent transcriptional activation and may function as an oncoprotein. Isoform 2 acts as a negative growth regulator by cooperating with p53 in transcriptional activation of p53-responsive genes and may act as a tumor suppressor.[UniProtKB/Swiss-Prot Function]

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