Mouse Nrep activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nrep
Locus ID	27528
Kit Components	GA205174G1, Nrep gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205174G2, Nrep gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205174G3, Nrep gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001109988, NM_001109989, NM_001109990, NM_001267717, NM_053078
Synonyms	AI325076; D0H4S114; Harp; P311; PTZ17; SEZ17
Summary	May have roles in cellular differentiation. Ectopic expression induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. May also have neural functions. Promotes axonal regeneration and augments motility of gliomas. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation.[UniProtKB/Swiss-Prot Function]

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