Mouse Ndrg2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ndrg2
Locus ID	29811
Kit Components	GA205227G1, Ndrg2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205227G2, Ndrg2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205227G3, Ndrg2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001145959, NM_013864, NM_001360264, NM_001360269, NM_001360270, NM_001360272, NM_001360274, NM_001360276, NM_001360265, NM_001360266, NM_001360267, NM_001360268, NM_001360271, NM_001360273
Synonyms	AI182517; AU040374; Ndr2; SYLD
Summary	Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).[UniProtKB/Swiss-Prot Function]

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