Mouse Keap1 activation kit by CRISPRa
CAT#: GA205381
Keap1 CRISPRa kit - CRISPR gene activation of mouse kelch-like ECH-associated protein 1
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Keap1 |
Locus ID | 50868 |
Kit Components | GA205381G1, Keap1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205381G2, Keap1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205381G3, Keap1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001110305, NM_001110306, NM_001110307, NM_016679 |
Synonyms | INRF2; mKIAA0132 |
Summary | Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN308748 | Keap1 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN308748BN | Keap1 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN308748LP | Keap1 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN308748RB | Keap1 - mouse gene knockout kit via CRISPR, HDR mediated |
CNY 12,260.00 |
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KN508748 | Keap1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |