Mouse Tnfsf14 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tnfsf14
Locus ID	50930
Kit Components	GA205404G1, Tnfsf14 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205404G2, Tnfsf14 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205404G3, Tnfsf14 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_019418
Synonyms	HVEM-L; HVEML; LIGHT; LTg; Ly113; Tnlg1d
Summary	Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB and stimulates the proliferation of T-cells. Acts as a ligand for TNFRSF14/HVEM. Upon binding to TNFRSF14/HVEM, delivers costimulatory signals to T cells, leading to T cell proliferation and IFNG production (By similarity).[UniProtKB/Swiss-Prot Function]

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