Mouse Porcn activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Porcn
Locus ID	53627
Kit Components	GA205598G1, Porcn gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205598G2, Porcn gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205598G3, Porcn gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001308474, NM_016913, NM_023638, NM_145907, NM_145908, NR_131893
Synonyms	2410004O13Rik; AW045557; DXHXS7465e; Mg61; mMg61; Mporc; porc; Ppn
Summary	Protein-serine O-palmitoleoyltransferase that acts as a key regulator of the Wnt signaling pathway by mediating the attachment of palmitoleate, a 16-carbon monounsaturated fatty acid (C16:1), to Wnt proteins. Serine palmitoleylation of WNT proteins is required for efficient binding to frizzled receptors.[UniProtKB/Swiss-Prot Function]

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