Mouse Caprin1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Caprin1
Locus ID	53872
Kit Components	GA205610G1, Caprin1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205610G2, Caprin1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205610G3, Caprin1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001111289, NM_001111290, NM_001111291, NM_001111292, NM_016739
Synonyms	AL022980; Caprin-1; Gpiap; Gpiap1; Mmgpip137; P137; rng105
Summary	May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types (PubMed:20516077). Binds directly and selectively to MYC and CCND2 RNAs. In neuronal cells, directly binds to several mRNAs associated with RNA granules, including BDNF, CAMK2A, CREB1, MAP2, NTRK2 mRNAs, as well as to GRIN1 and KPNB1 mRNAs, but not to rRNAs (By similarity).[UniProtKB/Swiss-Prot Function]

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