Mouse Epb41l4b activation kit by CRISPRa
CAT#: GA205679
Epb41l4b CRISPRa kit - CRISPR gene activation of mouse erythrocyte membrane protein band 4.1 like 4b
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Epb41l4b |
Locus ID | 54357 |
Kit Components | GA205679G1, Epb41l4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205679G2, Epb41l4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205679G3, Epb41l4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_019427, NM_001355492 |
Synonyms | 6430543G08Rik; AA589614; AU021054; BB007528; D4Ertd346e; Ehm2; Epb4.1l4b; Lulu2 |
Summary | Up-regulates the activity of the Rho guanine nucleotide exchange factor ARHGEF18 (PubMed:22006950). Involved in the regulation of the circumferential actomyosin belt in epithelial cells (PubMed:22006950). Promotes cellular adhesion, migration and motility in vitro and may play a role in wound healing (By similarity). May have a role in mediating cytoskeletal changes associated with steroid-induced cell differentiation (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505265 | Epb4.1l4b - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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