Mouse Dll4 activation kit by CRISPRa
CAT#: GA205720
Dll4 CRISPRa kit - CRISPR gene activation of mouse delta like canonical Notch ligand 4
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Dll4 |
Locus ID | 54485 |
Kit Components | GA205720G1, Dll4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205720G2, Dll4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205720G3, Dll4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_019454 |
Synonyms | Delta4 |
Summary | Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (By similarity). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (PubMed:22323600). During spinal cord neurogenesis, inhibits V2a interneuron fate (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
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KN304622 | Dll4 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN304622LP | Dll4 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN304622RB | Dll4 - mouse gene knockout kit via CRISPR, HDR mediated |
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KN504622 | Dll4 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
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