Mouse Tyk2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tyk2
Locus ID	54721
Kit Components	GA205768G1, Tyk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205768G2, Tyk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205768G3, Tyk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001205312, NM_018793
Synonyms	JTK1
Summary	Involved in intracellular signal transduction by amplifying type I and type II IFN signaling. Phosphorylates the interferon-alpha/beta receptor alpha chain. Plays an essential role in promoting selective immune responses, including innate host defense mechanisms and specific antiviral activities.[UniProtKB/Swiss-Prot Function]

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