Mouse Trim3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trim3
Locus ID	55992
Kit Components	GA205801G1, Trim3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205801G2, Trim3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205801G3, Trim3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001285870, NM_001285871, NM_001285873, NM_018880, NM_001360425
Synonyms	BERP1; HAC1; Rnf22
Summary	Probably involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation (By similarity). Positively regulates motility of microtubule-dependent motor protein KIF21B (PubMed:24086586).[UniProtKB/Swiss-Prot Function]

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