Mouse Ube4b activation kit by CRISPRa

CAT#: GA206421

Ube4b CRISPRa kit - CRISPR gene activation of mouse ubiquitination factor E4B



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CNY 12,255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Ube4b
Locus ID 63958
Kit Components

GA206421G1, Ube4b gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206421G2, Ube4b gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206421G3, Ube4b gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_022022
Synonyms 4930551I19Rik; 4933406G05Rik; AU014668; D4Bwg0973e; mKIAA0684; UFD2; UFD2a; Ufd2p
Summary Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (PubMed:11435423). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (By similarity).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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