Mouse Map3k20 activation kit by CRISPRa
CAT#: GA206531
Map3k20 CRISPRa kit - CRISPR gene activation of mouse mitogen-activated protein kinase kinase kinase 20
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Map3k20 |
Locus ID | 65964 |
Kit Components | GA206531G1, Map3k20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206531G2, Map3k20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206531G3, Map3k20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001164791, NM_023057, NM_178084 |
Synonyms | AV006891; B230120H23Rik; MLTK; MLTKalpha; MLTKbeta; Zak |
Summary | Stress-activated component of a protein kinase signal transduction cascade. Regulates the JNK and p38 pathways (PubMed:11042189). Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14 (By similarity). Pro-apoptotic. Role in regulation of S and G2 cell cycle checkpoint by direct phosphorylation of CHEK2 (By similarity). Involved in limb development (PubMed:26755636).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN519580 | Map3k20 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |
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