Mouse Rassf7 activation kit by CRISPRa
CAT#: GA207065
Rassf7 CRISPRa kit - CRISPR gene activation of mouse Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Rassf7 |
Locus ID | 66985 |
Kit Components | GA207065G1, Rassf7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207065G2, Rassf7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207065G3, Rassf7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_025886 |
Synonyms | 2400009B11Rik; AW210608 |
Summary | Negatively regulates stress-induced JNK activation and apoptosis by promoting MAP2K7 phosphorylation and inhibiting its ability to activate JNK. Following prolonged stress, anti-apoptotic effect stops because of degradation of RASSF7 protein via the ubiquitin-proteasome pathway. Required for the activation of AURKB and chromosomal congression during mitosis where it stimulates microtubule polymerization (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN514521 | Rassf7 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |