Mouse Pdcl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdcl
Locus ID	67466
Kit Components	GA207347G1, Pdcl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207347G2, Pdcl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207347G3, Pdcl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_026176
Synonyms	1200011E13Rik; AW108059; PhLP1
Summary	Functions as a co-chaperone for CCT in the assembly of heterotrimeric G protein complexes, facilitates the assembly of both Gbeta-Ggamma and RGS-Gbeta5 heterodimers (PubMed:23637185). Acts also as a positive regulator of hedgehog signaling and regulates ciliary function (PubMed:29290584).[UniProtKB/Swiss-Prot Function]

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