Mouse Rabl3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rabl3
Locus ID	67657
Kit Components	GA207443G1, Rabl3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207443G2, Rabl3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207443G3, Rabl3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001042499, NM_026297
Synonyms	4930553C05Rik; AA958834
Summary	Required for KRAS signaling regulation and modulation of cell proliferation (PubMed:31406347). Regulator of KRAS prenylation, and probably prenylation of other small GTPases (By similarity). Required for lymphocyte development and function (PubMed:32220963). Not required for myeloid cell development (PubMed:32220963).[UniProtKB/Swiss-Prot Function]

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