Mouse Tab2 activation kit by CRISPRa
CAT#: GA207884
Tab2 CRISPRa kit - CRISPR gene activation of mouse TGF-beta activated kinase 1/MAP3K7 binding protein 2
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Tab2 |
Locus ID | 68652 |
Kit Components | GA207884G1, Tab2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207884G2, Tab2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207884G3, Tab2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_138667, NM_001359534 |
Synonyms | 1110030N06Rik; A530078N03Rik; Map3k7ip2; mKIAA0733 |
Summary | Adapter linking MAP3K7/TAK1 and TRAF6. Promotes MAP3K7 activation in the IL1 signaling pathway. The binding of 'Lys-63'-linked polyubiquitin chains to TAB2 promotes autophosphorylation of MAP3K7 at 'Thr-187' (By similarity). Regulates the IL1-mediated translocation of NCOR1 out of the nucleus. Involved in heart development (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN517118 | Tab2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |